Link to University's homepage
Link to University's Finnish homepage
 
AAV Gene Transfer and Cell Therapy Core Facility

Contact Information:

Andrey Anisimov


Tanja Laakkonen


Visiting address:
Biomedicum Helsinki
Room A518
Haartmaninkatu 8
00290 Helsinki

Postal address:
Research Programs Unit
P.O. Box 63
FI-00014 University of Helsinki
Finland

Tel. +358 9 19125562
GSM +358 415317958

e-mail :
firstname.surname@helsinki.fi

Welcome to AAV Gene Transfer and Cell Therapy Core Facility

The Biomedicum AAV Core Facility provides services for manufacturing recombinant adeno-associated virus (AAV) preps from the customer’s gene-encoding plasmids. AAVs are able to transduce both dividing and non-dividing cells, does not provoke insertional mutagenesis and possesses very low immunogenicity.

Currently we produce AAVs of 4 different serotypes (AAV-2, 6, 8 and 9). Final virus preps are quantified and functionally characterized for the transgene expression (normally by western blotting, ELISA or fluorescent signal detection).

There are several ready AAV preps, immediately available on demand. These encode EGFP, Luciferase, LacZ, HSA, Fc part of mouse IgG, various growth factors and soluble receptors or were produced using an empty plasmid vector for the negative control.

Current prices: internal academic and HUS customers: € 676; external academic customers: € 1050 and external non-academic customers: € 1397.

We also consult the customers (free of charge) for the optimal design of AAV vectors, which would carry the customer’s transgene.