Salven groups's website has moved.

http://www.hi.helsinki.fi/english/research/pathology.html

Stem cell research is presently one of the most exciting areas of modern biology. Stem cells are the source of all tissues of the body. Harnessing the potential of these cells may make it possible to develop new treatments for many regenerative diseases by replacing cells that are lost or damaged in the disease process. We also need to dissect the molecular machinery governing stem cell functions to understand and target diseases such as cancer.
The primary mission of our lab is the discovery and validation of new mechanisms of stem cell self-renewal and differentiation. Understanding of these mechanisms at the molecular level will eventually lead to methods to change cells of one phenotype to another as a means of providing histocompatible cells for cell therapies, as well as to methods to inhibit cancer growth. To achieve this goal, we use innovative functional genomics methods to identify and functionally test genes and molecules that regulate stem cells, and evaluate their importance by using in vivo mouse models. We are currently especially interested in the mechanisms governing adult stem cell functions during angiogenesis and cancer growth. Another important novel venture is high throughput differentiation screening of established murine and human embryonic stem (ES) cell lines to analyze factors responsible for differentiation of ES cells to mature cell or tissue types of biomedical importance.

Salven Lab News and Events:

• SUOMEN KUVALEHTI 28.10.2012: Syöpäkasvain voi kuolla nälkään
• Researchers track down stem cells in blood vessel walls
  News Link. Read the article. Read the article synopsis. Press release.
• HELSINGIN SANOMAT 18.10.2012: Suomalaiset löysivät uusia kantasoluja.
  
• AAMULEHTI 17.10.2012: Suomalaistutkijat löysivät avun syöpään yllättävästä
  paikasta.
• YLE UUTISET 17.10.2012: Kantasolulöytö avaa uusia mahdollisuuksia
  sairauksien hoidossa.
  
• University of Heidelberg Seminar Series, October 19, 2012, Heidelberg, Germany.
  Petri Salven: Adult vascular endothelial stem cells (VESCs)
• Joint meeting 2009 of the GfMVB (Gesellschaft für Mikrozirkulation und Vaskuläre Biologie) and the Swiss Society for Microcirculation (SSM), October 8-10, 2009, Berne, Switzerland.
  Petri Salven: Stem cells in postnatal angiogenensis
• 2nd International Kloster-Seeon meeting: 'The tumor - vessel interface': Cellular and molecular mechanisms of tumor progression and metastasis, September 19-22, 2009, Kloster-Seeon, Germany.
  Petri Salven: Bone marrow derived progenitor cells in angiogenesis and tumor growth.
• Stem Cells in the Vasculature – the 59th Annual British Microcirculation Society Meeting - March 30-31, 2009, University of  Birmingham, UK.
  Petri Salven: Stem Cells in Tumour Angiogenesis
• Biocenter Oulu Day 2009: Towards Understanding Cancer, March 17, 2009, University of Oulu, Finland.
  Petri Salven: Stem cells in cancer and angiogenesis
• Recent highlights of EU-funded medical research projects: Provided by CORDIS, the official information service for participation in the EU research programmes. New Biotechnology, Vol. 25, 2008.
• From Stem Cells to Therapy - Finnish Red Cross Blood Service 60th Anniversary Symposium, October 8th, 2008, Espoo, Finland.
  Petri Salven: Cancer and Stem Cells: Novel Prospects for Tumor Therapy
• HELSINGIN SANOMAT 9.5.2008: Suomalaisryhmä: Syöpähoitoja kehitelty tutkimalla kuvitteellisia kantasoluja
• TURUN SANOMAT 08.05.2008: Suomalaisjohtoinen tutkimus paljastaa väärinkäsityksiä: Uusia syöpähoitoja kehitelty tutkimalla kuviteltuja kantasoluja.
• HELSINGIN SANOMAT 29.04.2008: Kantasolut eivät ehkä kasvatakaan syöpäsuonistoa.
• ScienceDaily 24.04.2008: Stem Cell Type Supposed To Be Crucial For
  Angiogenesis And Cancer Growth Does Not Exist?
• A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist? Press release. Read an article in University's www-page (the article in Finnish) . The publication: Purhonen S., Palm J., Rossi D., Kaskenpää, N., Rajantie I., Ylä-Herttuala S., Alitalo K., Weissman I.L., and Salven P. Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci USA. Read the article.
• YLE Radio 1 Tiedeuutiset 23.04.2008: Syöpäkudos, kantasolut ja verisuonet - onko näillä yhteyttä vai ei?
• Academic dissertation: 14.12. 2007: Kuuliala (Anttonen), Krista: Innate immunity and its control in the pathogenesis of inflammatory rheumatic diseases. Supervisors Heikki Repo, Arto Orpana and Petri Salven.
• GSBM Cancer Biology, 11.12.2007 Biomedicum Helsinki, Small Lecture Room
• Salven Lab & Taipale Lab Summer Summit Meeting 16.08.2007, Restaurant Michelle, Helsinki, Finland
• Seventh ESH Euroconference on ANGIOGENESIS May 13, 2007 , Albufeira, Portugal: Susanna Purhonen: Analysis of bone marrow-derived cell endothelial differentiation capacity in vivo.
• Tieteen Päivät 2007 - Pe 12.01. 2007 klo 15:00:
  Petri Salven: Kantasolut syövässä
• GSBM Cancer Biology 21-22.11.2006
• Nyrjähtänyt kantasolu sysää syövän liikkeelle?
• 20th Anniversary Symposium of the Finnish Cancer Institute - STEM CELLS AND CANCER, photo
• Understanding Tumor-host Interactions, Five European Labs Cooperate
• Tumor cell growth depends on interactions with its microenvironment
• Suomalaisten koordinoima EU-hanke tähtää uudenlaisiin syövän täsmälääkkeisiin
• Tutkijat etsivät keinoja katkaista syövän viestintäyhteydet
• Esteitä syövälle - Syövän biologian huippuyksikkö

Page updated February 13, 2015

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