Contact Information:
Kari Alitalo
M.D., Ph.D., Academy Professor
Molecular Cancer Biology Program
Biomedicum Helsinki
Haartman Institute
PO Box 63 (Haartmaninkatu 8)
FI-00014 University of Helsinki
Finland
Tel. +358 9 191 25511
Fax. +358 9 191 25510
e-mail :
firstname.surname@helsinki.fi
Administration:
Riikka Pahkala
Suvi Kilpeläinen
| 
|
Selected publications
- Jeltsch, M., Kaipainen, A., Joukov, V., Meng, X., Lakso, M., Rauvala, H., Swartz, M., Fukumura, D., Rakesh, K.J. and Alitalo, K.: Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276: 1423-1425, 1997.
- Dumont, D.J., Jussila, L., Taipale, J., Lymboussaki, A., Mustonen, T., Pajusola, K., Breitman, M. and Alitalo, K. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 282: 946-949, 1998.
- Karkkainen, M.J., Ferrell, R.E., Lawrence, E.C., Kimak, M.A., Levinson, K.L., McTigue, M.A., Alitalo, K. and Finegold, D.N.: Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema. Nature Genetics 25: 153-159, 2000.
- Mäkinen, T., Jussila, L., Veikkola, T., Kärpänen, T., Kettunen, M.I., Pulkkanen, K.J., Kauppinen, R., Jackson, D.G., Kubo, H., Nishikawa, S.-I., Ylä-Herttuala, S. and Alitalo, K.: Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nature Medicine 7: 199-205, 2001.
- He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T, Alitalo K. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling. J Natl Cancer Inst. 94: 819-25, 2002.
- Kärkkäinen, M.J., Haiko, P., Sainio, K., Partanen, J., Taipale, J., Petrova, T., Jeltsch, M., Jackson, D. G., Talikka, M., Rauvala, H., Betsholtz, C., and Alitalo, K. VEGF-C is required for sprouting of the first lymphatic vessels from embryonic veins. Nature Immunology 2004 Jan;5(1):74-80.
- Tammela T, et al. Nature medicine
Page updated
January 9, 2008
Mail to Webmaster |
