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Kari Alitalo - Tutkijatohtorit

Tutkijatohtorit (aikajärjestyksessä)

  • 1990-1996 Bergman, Mathias[1][2]
  • 1990-1992 Aprelikova, Olga[3]
  • 1992-1994 Tamagnone, Luca[4][5]
  • 1992-1997 Joukov, Vladimir[6][7][8][9]
  • 1995-1997 Taira, Suvi[10]
  • 1996-1998 Kumar, Vijay[8]
  • 1996-1999 Gunji, Yugi[11]
  • 1996-1997 Korpelainen, Eija[12][13]
  • 1997-1998 Taipale, Jussi[14]
  • 1999-2004 Petrova, Tatiana V.[15][16]
  • 11/2000-05/2005 He, Yulong[17][18][19]
  • 2000-2002 Kubo, Hajime[20]
  • 2002-07/2009 Saharinen, Pipsa[21][22][23]
  • 2003-2007 Pajusola, Katri[24]
  • 2004-04/2010 Heckman, Caroline[25]
  • 04/2006-05/2008 Holnthoner, Wolfgang[26]
  • 01/2007-06/2008 Kaijalainen, Seppo[27]
  • 04/2008-01/2009 Bromann, Paul
  • 04/2009-08/2011 Yamamoto, Masahiro[28]
  • 01/2003- Jeltsch, Michael[29][30]
  • 11/2006- Leppänen, Veli-Matti [31][30]
  • 03/2007- Anisimov, Andrey[27]
  • 01/2008- Tvorogov, Denis[32]
  • 05/2008- Kivelä, Riikka[33]
  • 07/2008-09/2011 Tammela, Tuomas[34]
  • 09/2008- D'Amico, Gabriela[35]
  • 02/2009- Wiener, Zoltan
  • 03/2011-01/2013 Kaijalainen, Seppo
  • 08/2011-06/2012 Öhman, Miina
  • 01/2012- Band, Arja
  • 08/2012- Robciuc, Marius

References

  1. Bergman, M., Mustelin, T., Oetken, C., Partanen, J., Flint, N.A., Amrein, K.E., Autero, M., Burn, P. & Alitalo, K.: The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity 1992. Viitattu 13.09.2011.
  2. Bergman, M., Joukov, V., Virtanen, I. & Alitalo, K.: Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading 1995. Viitattu 13.09.2011.
  3. Aprelikova, O., Pajusola, K., Partanen, J., Armstrong, E., Alitalo, R., Bailey, S.K., McMahon, J., Wasmuth, J., Huebner, K. & Alitalo, K.: FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter 1992. Viitattu 13.09.2011.
  4. Tamagnone, L., Partanen, J., Armstrong, E., Lasota, J., Ohgami, K., Tazunoki, T., LaForgia, S., Huebner, K. & Alitalo, K.: The human ryk cDNA sequence predicts a protein containing two putative transmembrane segments and a tyrosine kinase catalytic domain 1993. Viitattu 13.09.2011.
  5. Tamagnone, L., Lahtinen, I., Mustonen, T., Virtaneva, K., Francis, F., Muscatelli, F., Alitalo, R., Smith, C.I., Larsson, C. & Alitalo, K.: BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2 1994. Viitattu 13.09.2011.
  6. Joukov, V., Pajusola, K., Kaipainen, A., Chilov, D., Lahtinen, I., Kukk, E., Saksela, O., Kalkkinen, N. & Alitalo, K.: A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases 1996. Viitattu 13.09.2011.
  7. Joukov, V., Vihinen, M., Vainikka, S., Sowadski, J.M., Alitalo, K. & Bergman, M.: Identification of csk tyrosine phosphorylation sites and a tyrosine residue important for kinase domain structure 1997. Viitattu 13.09.2011.
  8. Joukov, V., Sorsa, T., Kumar, V., Jeltsch, M., Claesson-Welsh, L., Cao, Y., Saksela, O., Kalkkinen, N. & Alitalo, K.: Proteolytic processing regulates receptor specificity and activity of VEGF-C 1997. Viitattu 13.09.2011.
  9. Joukov, V., Kumar, V., Sorsa, T., Arighi, E., Weich, H., Saksela, O. & Alitalo, K.: A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability activities 1998. Viitattu 13.09.2011.
  10. Kukk, E., Lymboussaki, A., Taira, S., Kaipainen, A., Jeltsch, M., Joukov, V. & Alitalo, K.: VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development 1996. Viitattu 13.09.2011.
  11. Kukk, E., Wartiovaara, U., Gunji, Y., Kaukonen, J., Bühring, H.J., Rappold, I., Matikainen, M.T., Vihko, P., Partanen, J., Palotie, A. et al.: Analysis of Tie receptor tyrosine kinase in haemopoietic progenitor and leukaemia cells 1997. Viitattu 13.09.2011.
  12. Korpelainen, E.I., Karkkainen, M.J., Tenhunen, A., Lakso, M., Rauvala, H., Vierula, M., Parvinen, M. & Alitalo, K.: Overexpression of VEGF in testis and epididymis causes infertility in transgenic mice: evidence for nonendothelial targets for VEGF 1998. Viitattu 13.09.2011.
  13. Korpelainen, E.I., Kärkkäinen, M., Gunji, Y., Vikkula, M. & Alitalo, K.: Endothelial receptor tyrosine kinases activate the STAT signaling pathway: mutant Tie-2 causing venous malformations signals a distinct STAT activation response 1999. Viitattu 13.09.2011.
  14. Dumont, D.J., Jussila, L., Taipale, J., Lymboussaki, A., Mustonen, T., Pajusola, K., Breitman, M. & Alitalo, K.: Cardiovascular failure in mouse embryos deficient in VEGF receptor-3 1998. Viitattu 13.09.2011.
  15. Petrova, T.V., Mäkinen, T., Mäkelä, T.P., Saarela, J., Virtanen, I., Ferrell, R.E., Finegold, D.N., Kerjaschki, D., Ylä-Herttuala, S. & Alitalo, K.: Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor 2002. Viitattu 13.09.2011.
  16. Petrova, T.V., Karpanen, T., Norrmén, C., Mellor, R., Tamakoshi, T., Finegold, D., Ferrell, R., Kerjaschki, D., Mortimer, P., Ylä-Herttuala, S. et al.: Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis 2004. Viitattu 13.09.2011.
  17. He, Y., Kozaki, K., Karpanen, T., Koshikawa, K., Yla-Herttuala, S., Takahashi, T. & Alitalo, K.: [ Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling] 2002. Viitattu 13.09.2011.
  18. He, Y., Rajantie, I., Ilmonen, M., Makinen, T., Karkkainen, M.J., Haiko, P., Salven, P. & Alitalo, K.: Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis 2004. Viitattu 13.09.2011.
  19. He, Y., Rajantie, I., Pajusola, K., Jeltsch, M., Holopainen, T., Yla-Herttuala, S., Harding, T., Jooss, K., Takahashi, T. & Alitalo, K.: Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels 2005. Viitattu 13.09.2011.
  20. Kubo, H., Cao, R., Brakenhielm, E., Mäkinen, T., Cao, Y. & Alitalo, K.: Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea 2002. Viitattu 14.09.2011.
  21. Saharinen, P., Kerkelä, K., Ekman, N., Marron, M., Brindle, N., Lee, G.M., Augustin, H., Koh, G.Y. & Alitalo, K.: Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2 2005. Viitattu 14.09.2011.
  22. Saharinen, P., Eklund, L., Miettinen, J., Wirkkala, R., Anisimov, A., Winderlich, M., Nottebaum, A., Vestweber, D., Deutsch, U., Koh, G.Y. et al.: Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts 2008. Viitattu 13.09.2011.
  23. Saharinen, P., Helotera, H., Miettinen, J., Norrmen, C., D'Amico, G., Jeltsch, M., Langenberg, T., Vandevelde, W., Ny, A., Dewerchin, M. et al.: Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development 2010. Viitattu 14.09.2011.
  24. Pajusola, K., Künnapuu, J., Vuorikoski, S., Soronen, J., André, H., Pereira, T., Korpisalo, P., Ylä-Herttuala, S., Poellinger, L. & Alitalo, K.: Stabilized HIF-1alpha is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer 2005. Viitattu 14.09.2011.
  25. Heckman, C.A., Holopainen, T., Wirzenius, M., Keskitalo, S., Jeltsch, M., Ylä-Herttuala, S., Wedge, S.R., Jürgensmeier, J.M. & Alitalo, K.: The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis 2008. Viitattu 14.09.2011.
  26. Petrova, T. V., Bono, P., Holnthoner, W., Chesnes, J., Pytowski, B., Sihto, H., Laakkonen, P., Heikkilä, P., Joensuu, H. & Alitalo, K.: VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors 2008. Viitattu 14.09.2011.
  27. Anisimov, A., Alitalo, A., Korpisalo, P., Soronen, J., Kaijalainen, S., Leppänen, V., Jeltsch, M., Ylä-Herttuala, S. & Alitalo, K.: Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle 2009. Viitattu 14.09.2011.
  28. Zheng, W., Tammela, T., Yamamoto, M., Anisimov, A., Holopainen, T., Kaijalainen, S., Karpanen, T., Lehti, K., Ylä-Herttuala, S. & Alitalo, K.: Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor 2011. Viitattu 14.09.2011.
  29. Jeltsch, M., Karpanen, T., Strandin, T., Aho, K., Lankinen, H. & Alitalo, K.: Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns 2006. Viitattu 15.09.2011.
  30. Leppänen, V., Jeltsch, M., Anisimov, A., Tvorogov, D., Aho, K., Kalkkinen, N., Toivanen, P., Ylä-Herttuala, S., Ballmer-Hofer, K. & Alitalo, K.: Structural determinants of vascular endothelial growth factor-D receptor binding and specificity 2006. Viitattu 15.09.2011.
  31. Leppänen, V., Prota, A. E., Jeltsch, M., Anisimov, A., Kalkkinen, N., Strandin, T., Lankinen, H., Goldman, A., Ballmer-Hofer, K. & Alitalo, K.: Structural determinants of growth factor binding and specificity by VEGF receptor 2 2010. Viitattu 15.09.2011.
  32. Tvorogov, D., Anisimov, A., Zheng, W., Leppänen, V., Tammela, T., Laurinavicius, S., Holnthoner, W., Heloterä, H., Holopainen, T., Jeltsch, M., Kalkkinen, N., Lankinen, H., Ojala, P. M. & Alitalo, K.: Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization 2010. Viitattu 15.09.2011.
  33. Bry, M., Kivelä, R., Holopainen, T., Anisimov, A., Tammela, T., Soronen, J., Silvola, J., Saraste, A., Jeltsch, M., Korpisalo, P., Carmeliet, P., Lemström, K. B., Shibuya, M., Ylä-Herttuala, S., Alhonen, L., Mervaala, E., Andersson, L. C., Knuuti, J. & Alitalo, K.: Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation 2010. Viitattu 15.09.2011.
  34. Tammela, T., Saaristo, A., Holopainen, T., Ylä-Herttuala, S., Andersson, L. C., Virolainen, S., Immonen, I. & Alitalo, K.: Photodynamic ablation of lymphatic vessels and intralymphatic cancer cells prevents metastasis 2011. Viitattu 15.09.2011.
  35. D'Amico, G., Korhonen, E. A., Waltari, M., Saharinen, P., Laakkonen, P. & Alitalo, K.: Loss of endothelial Tie1 receptor impairs lymphatic vessel development 2010. Viitattu 15.09.2011.
Page updated January 29, 2014 by Michael Jeltsch
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