Postdoctoral fellowships : One position open. Deadline Nov 15.2009

A postdoctoral position open in a project investigating the role of conserved polarity genes in tumor suppression. The project uses state-of art reverse genetics approaches, combining lentiviral genetic shRNA screens, 3D matrix-grown organoid cell cultures and in vivo transgenic mouse mammary glands. The project is in the interface of basic and translational research involving both high-profile academic and industry collaborators.
 
The project is part of Ministry of Education national development program "Education and Research in Nanosciences" and involves partnership with a privately funded Finnish pharmaceutical company. The postdoctoral fellow will be affiliated with Klefström laboratory, Genome-Scale Biology program & Institute of Biomedicine, University of Helsinki.
 
Suitable candidates have background in Genetics, Biochemistry, Biomedicine or Biomedical Engineering. Previous knowledge on the above techniques is desired. Especially previous experience with mouse models of human disease or in context of developmental processes is bonus for candidate. Experience on standard biochemistry and molecular biology techniques and cell culturing is required. Additional desired experience includes lentiviral shRNA transduction, DNA transfer vectors and inducible systems, confocal  fluorescence microscopy & imaging techniques, flow cytometry & FACS sorting, and background in cancer biology and signal transduction.
 
The successful candidate should hold a PhD or equivalent. The salary will be based on qualifications.
 
Qualified applicants should send an application, including informal cover letter, CV and the names of 2 referees to Docent Juha Klefstrom (e-mail juha.klefstrom@helsinki.fi). Please use a reference (in subject line of your e-mail): C3L postdoc 2009
 
The closing date for the applications is November 15, 2009.

Graduate studentships: 1 position open. Deadline for applications Nov 15 .2009

We consider applications for trainee positions in a project investigating the role of conserved polarity genes in tumor suppression (the project is described above) from exceptionally skilled and motivated candidates not holding PhD. The graduate project will be full time commitment to earn Ph.D in the Cancer Cell Circuitry Laboratory at Biomedicum Helsinki, University of Helsinki and the salary will be based on qualifications.
  
Suitable candidates have background in Genetics, Biochemistry, Biomedicine or Biomedical Engineering. Previous knowledge on the listed techniques is appreciated. Experience on standard molecular biology techniques and cell culturing is required. We will consider applications from graduate students who have already earned M.Sc as well as undergraduates e.g. “pro gradu students” who have finished most of the basic studies and will be able to work full time for pro gradu in the project and aim to graduate during late spring 2010.
 
Please send your CV, name of at least one (preferably two) referee and a short informal description of yourself to: Juha Klefstrom, Ph.D,

Email: juha.klefstrom@helsinki.fi
The deadline for applications is Nov 15.2009.