Research Group Principal Investigator

    Johan G Eriksson, Professor, Chief physician, MD, DMSc

    Tel.+358 2941 27557
    E-mail: johan.eriksson [at] helsinki.fi

    Institute of Clinical Medicine Department of General Practice and Primary Health Care, 407
    P.O. Box 20, Tukholmankatu 8 B 00014 University of Helsinki
    Finland

Diabetes and Obesity Research Program contact information

Postal Address
Research Programs Unit
Diabetes and Obesity
Research Program
P.O.Box 63, Haartmaninkatu 8
FI-00014 University of Helsinki
Finland

Visiting Address
Biomedicum 1
Haartmaninkatu 8
00290 Helsinki

Tel. +358 2941 911 (tel. exchange)
Fax + 358 2941 26382
Email name.lastname [at] helsinki.fi

IDentifying Early Factors In Syndrome X (IDEFIX)- Presentation

IDEFIX Group

Helsinki Birth Cohort Study (HBCS) 1934-44 is a unique birth cohort study including 13345 subjects in the epidemiological cohort. The cohort is a longitudinal study cohort with data throughout the life span including prenatal life, early childhood and later life. Besides extensive epidemiological data over 2000 subjects have been randomly selected for a clinical part. The subjects have been followed up clinically for over one decade with extensive phenotypic data available including metabolic data, dietary information as well as other lifestyle data. Psychological factors including personality, depression and anxiety has been focused upon. A GWAS has been performed on the HBCS.

The main aim of HBCS is to assess the importance of early life factor on later health outcomes taking into account adult lifestyle, socioeconomic factors and genetic factors. There are more than 100 original publications based on findings in the HBCS.

Research questions of importance for the present consortium include:
- Importance of early growth for later risk of type 2 diabetes and obesity.
- The long-term consequences of maternal overweight and obesity for offspring later metabolic and cardiovascular health.
- Gene-early environmental interactions in development of obesity and related metabolic diseases.
- Factors influencing physical functioning in later life from a life course perspective.
- The studying of longevity for a life course perspective
- Early life stress and later metabolic health in former war evacuees
- Importance of epigenetic factors in development of obesity and other metabolic outcomes.

The HBCS group has built up an extensive national and internal network of collaborators that enables maximization of the resources for the epidemiological and genetic studies, but also for sharing of data and collaboration.