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The role of GATA factors in development and disease

 

Contact Information:

Markku Heikinheimo
M.D., Ph.D.
pediatrician, pediatric hematologist, Professor of Pediatrics

Head of the National Clinical Graduate School

Head of the Clinical Graduate School in Pediatrics and Obstetrics/Gynecology (PEGY) (co-chaired with prof. Jorma Paavonen)

Laboratory:
Biomedicum Helsinki 2U
P.O. Box 63 (Tukholmankatu 8)
00014 University of Helsinki
Finland

Office:
Children's Hospital
P.O. Box 22
00014 University of Helsinki
Finland

Tel. +358 9 471 71983
Fax +358 9 471 71947

E-mail:
firstname.surname@helsinki.fi

Visiting professor of pediatrics, Division of Pediatric
Hematology / Oncology,
Dept. of Pediatrics,
Washington University
Medical School,
St. Louis, MO, USA

 

Members of the Group

 

 

Group Leader,
Professor
Markku Heikinheimo
M.D.-Ph.D. 

TUHAT

LLab members

CContact tel. +358 9 471 71975

Leila Unkila-Kallio

Leila (M.D., PhD) is the clinical collaborator of the group and a senior consultant in gynecologic endocrinology, obstetrics and gynaecology in the Helsinki University Central Hospital. Her research focuses on clinical aspects of granulosa cell tumors, infertility and growth factors. Leila is the co-supervisor of Anniina´s thesis project.

TUHAT

Publications

Mikko Anttonen

Mikko (M.D., PhD) is a resident and research fellow at the Dept. of Obstetrics and Gynecology (HUCH). His translational research focuses on diseases involving dysfunction of the ovarian granulosa cells, particularly granulosa cell tumors (GCT), and ovarian hyperstimulation syndrome (OHSS) that occurs during infertility treatments. His major goal is to clarify how FOXL2 and anti-Müllerian Hormone (AMH) are linked to the pathogenesis and the clinical behavior of these diseases. Mikko is the co-supervisor of Marjut's and Anniina´s thesis projects.

E-thesis

Publications

Noora Andersson

Noora Andersson (PhD) is a cell biologist working as a post-doc in the lab. She graduated from the University of Helsinki in 2008. Her research concerns the impact of epidermal growth factor receptor family members and their multiple signaling pathways in the pathogenesis of adult human granulosa cell tumors.

E-thesis

Publications

Antti Kyrönlahti

Antti (M.D. PhD) defended his thesis on Feb 2011. His thesis focused on the role of GATA4 and apoptotic TRAIL pathway in granulosa cell function and tumors. Next, he will join Tea to study the role of GATA4 in childhood liver tumors.

E-thesis

Publications

Anniina Färkkilä

Anniina (M.D.) is specializing in obstetrics and gynecology and her research is focused on angiogenic growth factors and Anti-Müllerian Hormone in granulosa cell tumors, with additional focus on the clinical aspects of granulosa cell tumor patients.

Publications

Marjut Pihlajoki

Marjut (M.Sc.) is a physiologist. She has graduated from the University of Helsinki in 2010. Her research has focused on the pathobiology of ovarian granulosa cell tumors with special emphasis on the molecular pathogenesis and new treatment modalities of this disease.

Publications

Helka Parviainen

Helka (M.D.) studies GATA factors in the adrenal cortex and the ovary. Her focus is in their function and cofactors in normal vs. dysplastic tissue. She is also interested in the role of these factors in adrenogonadal development. Helka is a Ph.D. student in PEGY graduate school.

Publications

Tea Soini

Tea is an undergraduate M.D.- PhD student. Her reseach is focused on the role of GATA factors in liver development and pediatric liver cancer.

Publications

Sanna Vattulainen

Sanna is an undergraduate student from the Faculty of Biological Sciences. She is finishing her Master's thesis project that concentrates on the novel granulosa cell tumor specific FOXL2 mutation (C134W) and its interaction with GATA4 transcription factor in GCT biology.

Taru Jokinen

Taru has worked as the group's technician since '04. Her skills and knowlegde about different protein and mRNA detection methods, and cell cultures have been valuable for the group researchers.

L Previous members

Ilkka Ketola

Ilkka is (M.D., PhD) currently specializing in pediatrics in HUCH. Ilkka was the first to defend his thesis in the group of Friends of GATA (FOG´s) year ´03. The topic of his thesis was the role of GATA factors during testicular development and diseases.

E-thesis

Publications

Sanne Kiiveri

Sanne (M.D., PhD) works currently as a pediatrician in HUCH, Jorvi Hospital. Her main interest is the transcriptional regulation of adrenocortical development and function. She has also studied the hormonal and transcriptional changes leading to adrenocortical tumor formation concentrating on the roles of GATA-4, GATA-6 and LH receptor.

E-thesis

Publications

 

Susanna Mannisto

Susanna (M.D., PhD) defended her thesis autumn ´05. Her research topic was about the role of GATA transcription factors in endodermal development and germ cell tumors. She is interested in the factors programming embryonic stem cell differentiation towards endoderm. Currently, Susanna is specializing in concology at the HUCH department of Oncology.

E-thesis

Publications

 

Hanna Haveri

Hanna (M.D., PhD) defended her thesis autumn '08. She has studied GATA factors in inflammation, enzymatic malfunction and tumors of the digestive organs. She is currently specializing in neurology in HUCH.

E-thesis

Jonna Salonen

Jonna (M.D., PhD.) is currently specializing in obstetrics and gynecology. She defended her thesis 2009. The topic of her thesis was biology and tumor markers of malignant ovarian and testicular germ cell tumors.

E-thesis

Publications

 

Page updated September 21, 2011

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