Sigrid Jusélius Symposium
Translation of Immunity, Inflammation and Cancer Mechanisms
Sunday June 11
| Welcome session |
| Chairs: Kari Alitalo & Riitta Lahesmaa |
| 17:00 | Sirpa Jalkanen: Opening words | |
| Sigrid Jusélius Foundation | ||
| 17:05 | Kari Alitalo, Heikki Joensuu & Riitta Lahesmaa: Welcome | |
| Organizing committee | ||
| 17:10 | Ira Mellman: Oncology meets immunology in drug development | |
| Genentech, San Francisco CA | ||
| 17:50 | Anjana Rao: TET methylcytosine oxidases, immune responses and cancer | |
| La Jolla Institute for Allergy and Immunology, La Jolla CA | ||
| 18:30 | Welcome reception |
Monday June 12
| Session 1: Stem cells in cancer |
| Chair: Tomi Mäkelä |
| 8:30 | David Scadden: Heterogeneity in the making of blood | |
| Harvard & Massachusetts General Hospital | ||
| 9:05 | Eduard Batlle: Mechanisms of immune evasion and metastasis in colorectal cancer | |
| Institute for Research in Biomedicine, Barcelona | ||
| 9:40 | Frederic de Sauvage: Targeting intestinal stem cells in cancer | |
| Genentech, San Francisco CA | ||
| 10:15 | Coffee break/Press conference |
| Session 2: Regulatory networks and mouse models |
| Chair: Tuomas Tammela |
| 10:55 | Anton Berns: Mouse models of lung cancer | |
| Netherlands Cancer Institute, Amsterdam | ||
| 11:30 | Julien Sage: Intra-tumoral heterogeneity and response to therapy in SCLC | |
| Stanford University, Stanford CA | ||
| 12:05 | Lunch |
| Session 3: Signaling and regulation of the immune system |
| Chair: Riitta Lahesmaa |
| 13:15 | Hidde Ploegh: Imaging immunity | |
| Boston Children's Hospital, Boston MA | ||
| 13:50 | Jonathan Powell: Targeting metabolism to enhance cancer immunotherapy | |
| Johns Hopkins University, Baltimore MD | ||
| 14:25 | Coffee break | |
| 15.05 | Sankar Ghosh: NF-kB, inflammation and cancer | |
| Columbia University, New York NY | ||
| 15:40 | Micheal Sieweke: Epigenetic control of macrophage self renewal, identity and function | |
| Centre d'Immunologie de Marseille-Luminy, Marseille | ||
| Poster viewing |
| 16:15 | Poster viewing | |
| With refreshments |
| 18:00 | Speaker's archipelago cruise, by invitation only |
Tuesday June 13
| Session 3: New approaches |
| Chair: Harri Lähdesmäki |
| 8:30 | Mark Davis: Concerted mobilization of different T cell types in autoimmunity | |
| Stanford University, Stanford CA | ||
| 9:05 | Satu Mustjoki: Novel somatic mutations in patients with autoimmune disorders | |
| University of Helsinki, Helsinki | ||
| 9:40 | Patrick Hogan: Calcium channels and immune function - new tools and therapeutic opportunities | |
| La Jolla Institute for Allergy and Immunology, La Jolla CA | ||
| 10:15 | Coffee break |
| Session 4: Immune therapies |
| Chair: Mikael Knip |
| 10:55 | Roland Kolbeck: Targeting type-1 interferon for the treatment of autoimmune diseases | |
| MedImmune, Bethesda MD | ||
| 11:30 | Olli Silvennoinen: JAK kinases as therapeutic targets | |
| University of Tampere, Tampere | 12:05 | Lunch |
| Session 5: Cancer niches and stem cells |
| Chair: Kari Alitalo |
| 13:15 | Calvin Kuo: Organoid modeling of tumor-stroma interactions | |
| Stanford University, Stanford CA | ||
| 13:50 | Omer Yilmaz: Dietary control of stem cells and cancer in obesity | |
| Massachusetts Institute of Technology, Cambridge MA | ||
| 14:25 | Coffee break | |
| 15:05 | Tuomas Tammela: Investigating cellular heterogeneity in cancer | |
| Massachusetts Institute of Technology, Cambridge MA | ||
| 15:40 | Pekka Katajisto: Age-induced changes in the stem cell niche and intestinal regeneration | |
| University of Helsinki, Helsinki |
| Poster session |
| Chairs: Päivi Ojala & Mika Rämet |
| 16:00 | Moderated short communications & Best abstract award |
| 17:15 | Poster session | |
| With refreshments |
| 18:15 | Symposium dinner |
Wednesday June 14
| Session 7: Improving outcomes |
| Chair: Heikki Joensuu |
| 8:30 | Dieter Saur: Modeling and targeting pancreatic cancer and its microenvironment | |
| Technical University of Munich, Munich | ||
| 9:05 | Olli Kallioniemi: Systematic analysis of drug responses in patient-derived cancer cells | |
| Science for Life Laboratory, Karolinska Institutet, Stockholm | ||
| 9:40 | Pasi Jänne: Strategies to prevent and overcome resistance to EGFR inhibitors in lung cancer | |
| Dana-Farber Cancer Insitute, Boston MA | ||
| 10:15 | Coffee break |
| Session 8: Immune check-point therapy |
| Chair: Sirpa Jalkanen |
| 10:55 | Padmanee Sharma: From the clinic to the lab: investigating response and resistance mechanisms to immune checkpoint therapy | |
| University of Texas MD Anderson Cancer Center, Houston TX | ||
| 11:30 | James Allison: Immune checkpoint blockade in cancer therapy: new insights into mechanisms | |
| University of Texas MD Anderson Cancer Center, Houston TX | ||
| 12:05 | Heikki Joensuu: Closing remarks | |
| 12:20 | End |