• Molecular Cancer Biology Program
• Institute of Biomedicine
• HBGP - Helsinki Biomedical Graduate Program
• Nordic C. elegans Network
• COST Action BM0703 /CANGENIN

 

Contact Information:

Carina Holmberg-Still
Ph.D., Docent,
Academy Research Fellow
Molecular Cancer Biology Program
& Institute of Biomedicine Biomedicum Helsinki
PO Box 63 (Haartmaninkatu 8)
FI-00014 University of Helsinki
Finland

Tel. +358 9 191 25549
Fax. +358 9 191 25554

e-mail :
firstname.holmberg@helsinki.fi

Publications are accessed through PubMed 

Li X, Matilainen O, Jin C, Glover-Cutter KM, Holmberg CI*. and Blackwell TK*, Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity. PLoS Genet., 2011, 7:e1002119, (*joint corresponding author).

Hamer* G, Matilainen* O, Holmberg CI. A photoconvertible reporter of the ubiquitin-proteasome system in vivo. Nat Methods. 2010, 7:473-8, (*equal contribution).

Ryhänen T, Hyttinen JM, Kopitz J, Rilla K, Kuusisto E, Mannermaa E, Viiri J, Holmberg CI, Immonen I, Meri S, Parkkinen J, Eskelinen EL, Uusitalo H, Salminen A, Kaarniranta K. Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells. J Cell Mol Med. 2009, 13:3616-31.

Pispa J, Palmén S, Holmberg CI, Jäntti J. C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth. BMC Dev Biol. 2008, 8:51.

Matsumoto G, Stojanovic A, Holmberg CI, Kim S, Morimoto RI. Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates. J Cell Biol. 2005, 171:75-85.

Holmberg CI, Staniszewski KE, Mensah KN, Matouschek A, Morimoto RI. Inefficient degradation of truncated polyglutamine proteins by the proteasome. EMBO J. 2004, 23:4307-18.

Hietakangas V, Ahlskog JK, Jakobsson AM, Hellesuo M, Sahlberg NM, Holmberg CI, Mikhailov A, Palvimo JJ, Pirkkala L, Sistonen L. Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1.
Mol Cell Biol. 2003, 23:2953-68.

Holmberg CI, Hietakangas V, Mikhailov A, Rantanen JO, Kallio M, Meinander A, Hellman J, Morrice N, MacKintosh C, Morimoto RI, Eriksson JE, Sistonen L. Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1. EMBO J. 2001, 20:3800-10.

Page updated June 10, 2011

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