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Adult Stem Cells and Cancer

Affiliations:

Contact Information:

Petri Salven
M.D., Ph.D., Adjunct Professor

Molecular Cancer Biology Program
Biomedicum Helsinki
PO Box 63 (Haartmaninkatu 8)
FI-00014 University of Helsinki
Finland

Tel. +358 9 191 25384
Fax. +358 9 191 25664

e-mail :
firstname.surname@helsinki.fi

Selected publications
Salven group

Salven groups's website has moved.

http://www.hi.helsinki.fi/english/research/pathology.html

    • Fang S, Wei J, Pentinmikko N, Leinonen H, Salven P. (2012). Generation of
      Functional Blood Vessels from a Single c-kit+ Adult Vascular Endothelial
      Stem Cell. PLOS Biology 10(10): e1001407. doi:10.1371/journal.pbio.1001407
      Read the article. Read the article synopsis.
    • Fang S, Pentinmikko N, Ilmonen M, Salven P. (2012). Dual action of TGF-β induces vascular growth in vivo through recruitment of angiogenic VEGF-producing hematopoietic effector cells. Angiogenesis 15; 511-9. Read the article.
    • Fang S, Repo H, Joensuu H, Orpana A, Salven P. (2011). High serum angiogenin at
      diagnosis predicts for failure on long-term treatment response and for poor
      overall survival in non-Hodgkin lymphoma. Eur J Cancer 47; 1708-16. Read the article.
    • Fang S, Salven P. (2011) Stem cells in tumor angiogenesis. J Mol Cell Cardiol 50; 290-5. Read the article.
    • Purhonen S, Palm J, Rossi D, Kaskenpää N, Rajantie I, Ylä-Herttuala S, Alitalo K, Weissman I.L, Salven P. (2008). Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci USA. Read the article
    • He Y, Luo Y, Tang S, Rajantie I, Salven P, Heil M, Zhang R, Luo D, Li X, Chi H, Yu J, Carmeliet P, Schaper W, Sinusas AJ, Sessa WC, Alitalo K, Min W. (2006). Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis. J Clin Invest 116; 2344-55. Read the article.
    • Rajantie I, Ilmonen M, Alminaite A, Ozerdem U, Alitalo K, Salven P. (2004). Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells. Blood, 104; 2084-6. Read the article.
    • He Y, Rajantie I, Ilmonen M, Makinen T, Karkkainen M.J, Haiko P, Salven P, Alitalo K. (2004). Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis. Cancer Res 64; 3737-3740. Read the article.
    • Uutela M, Wirzenius M, Paavonen K, Rajantie I, He Y, Karpanen T, Lohela M, Wiig H, Salven P, Pajusola K, Eriksson U, Alitalo K. (2004). PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Blood 104; 3198-204. Read the article.
    • Salven P. and Alitalo R. (2004). Kantasolut ihmisen varaosina - huomispäivää vai huuhaata? Duodecim, 17; 7-9. Read the Finnish article.
    • Salven P, Mustjoki S, Alitalo R, Alitalo K, Rafii S. (2003). VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells. Blood 101; 168-172. Read the article.
    • Salven P, Hattori K, Heissig B, Rafii S. (2002). Interleukin-1a (IL-1a) promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion. FASEB J 16; 1471-1473. Read the article.

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