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Molecular Cancer Biology Program
Research groups


Infrastructure Development

The program uses a wide range of technologies necessary for internationally competitive and successful basic and translational biomedical research. Several core facilities received support or were set-up by MCB teams during the first term (2001-2006) and will be supported jointly by the MCB and GSB programs. These include Biomedicum Virus Core (BVC), Biomedicum Biochip Center (BBC), Biomedicum Sequencing Unit (BSU), High Throughput Center (HTC), Biomedicum Imaging Unit (BIU), Protein Interaction Facility, and Meilahti Transgenic Facility. BIU and BSU will be directly operational within the Molecular Cancer Biology Program. We will continue exploration and development of viral gene delivery systems, like lenti-, adeno-, and AAV-viruses in functional genomics approaches, cancer therapies, and in various animal models.

 Biomedicum Core Facilities

Biomedicum Sequencing Unit (BSU)

The core facility provides a sequencing service for DNA templates (plasmid DNA, PCR products). Sequencing reactions are analysed with an Applied Biosystems ABI Prism 3130xl 16 capillary Genetic Analyzer. The Facility offers standard primers, while special primers are provided by the customer. The unit services 30 groups on campus, including Biomedicum Helsinki, Haartman Institute and the hospital. Over 11 000 sequencing reactions were run in 2004. Contact: Tapio Tainola, E-mail:

Biomedicum Imaging Unit (BIU)

The Biomedicum Imaging Unit, provides expertise and state-of-the-art equipment for modern multi-dimensional imaging applications. Currently available imaging systems include confocal and wide-field high-speed microscopes, whole animal optical imaging and MRI, high content screening and image post-processing workstations. We provide services for user specific applications including image restoration and deconvolution, volume and surface reconstructions, animations and various quantitative image acquisition and analysis applications such as FRET and FRAP. These services are available for all researchers, irrespective of their locations or affiliations. BiU office and imaging platforms are located in Biomedicum. Total number of current users is 140. Contact by E-mail: bio-support[at]

Helsinki Functional Imaging Center (HFIC)

HFIC is a imaging center providing analysis tools, services and training for a wide scope of imaging methods including electron microscopy (EM), cryo-EM and tomography, scanning EM, a large set of fluorescence and light microscopy applications and small animal magnetic resonance imaging (MRI). These facilitate ultrastructural and structural analyses of molecules, organelles and materials, and respective molecular analyses of their functional and dynamic properties in live cells and animals in various biological, physiological and disease models.

HFIC integrates the activities of ten core facilities, several member laboratories and has 23 full-time support personnel. HFIC currently supports over 500 customers in the academia and commercial ventures all over Finland. These include end-users at four universities (Helsinki, Turku, Jyväskylä, Joensuu), two technical universities (Helsinki, Tampere), three private research institutes, the National Public Health Institute, Hospital District of Helsinki and Uusimaa (HUS) and abroad.

The aim of HFIC is to coordinate imaging activities in the Helsinki area, and to provide an user-friendly interphase for distribution of information on resources, activities and training. Its future key development areas include development of sophisticated image analysis tools and software utilizing mathematical modeling and computational image analysis.
Contact: Elina Ikonen, E-mail:

Äkta Explorer FPLC Core Facility

Contacts: Michael Jeltsch, E-mail: michael[at]
and Marko Hyytiäinen, E-mail:

AAV Core Facility

The Biomedicum AAV Core Facility provides services for manufacturing recombinant adeno-associated virus (AAV) preps from the customer¹s gene-encoding plasmids.
Contact: Andrey Anisimov and Tanja Laakkonen, E-mail:

Page updated November 22, 2011

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